Yes, especially when on considers the original purpose of tamegeshiri....which was sword cutting ability tested upon either living prisoners, or corpses.
Remember, when a Japanese daito cuts, it draws backwards on a cut instead of just hacking through like a European blade does. That's how it slices through what's in front of it. Now, that same principle applies with pushing cuts as well. The cutting edge meets it's object, and as it impacts, it's sliding on a slicing plane to cut through the object with applied friction on the cut.
Nowadays tamegeshiri is done by cutting rolled up mats of tatami (straw mats). It doesn't give nearly the same resistance as a body would....but it's still good to make sure you're cutting straight.
So, as another fellow mentioned above....if your taijutsu is correct in movement and the sword is moved with a solid stroke...they could quite easily sever the limbs or head of someone.
They can kill with shallow cuts as well, everyone seems to have an idea that all movements with a daito have to be some huge drawn-out stroke....which isn't even close to true.